Ausgewählte Publikationen / Selected publications

  1. Katahira S, Barth M, Döpp R, Sugimura Y, Schmidt V, Selig JI, Saiki Y, Jankowski J, Marx N, Jahnen-Dechent W, Lichtenberg A, Akhyari P. Pioglitazone treatment mitigates cardiovascular bioprosthetic degeneration in a chronic kidney disease model. Front Pharmacol. 2024 Aug 8;15:1412169.
  2. Immohr MB, Teichert HL, Dos Santos Adrego F, Schmidt V, Sugimura Y, Bauer SJ, Barth M, Lichtenberg A, Akhyari P. Three-Dimensional Bioprinting of Ovine Aortic Valve Endothelial and Interstitial Cells for the Development of Multicellular Tissue Engineered Tissue Constructs. Bioengineering (Basel). 2023 Jun 30;10(7):787.
  3. Katahira S, Sugimura Y, Grupp S, Doepp R, Selig JI, Barth M, Lichtenberg A, Akhyari P. PPAR-Gamma Activation May Inhibit the In Vivo Degeneration of Bioprosthetic Aortic and Aortic Valve Grafts under Diabetic Conditions. Int J Mol Sci. 2021 Oct 14;22(20):11081.
  4. Chekhoeva A, Nakanishi S, Sugimura Y, Toshmatova M, Assmann AK, Lichtenberg A, Akhyari P, Assmann A. Dichloroacetate inhibits the degeneration of decellularized cardiovascular implants. Eur J Cardiothorac Surg. 2021 Dec 27;61(1):19-26.
  5. Assmann AK, Goschmer D, Sugimura Y, Chekhoeva A, Barth M, Assmann A, Lichtenberg A, Akhyari P. A Role for Peroxisome Proliferator-Activated Receptor Gamma Agonists in Counteracting the Degeneration of Cardiovascular Grafts. J Cardiovasc Pharmacol. 2021 Oct 15;79(1):e103-e115.
  6. Sugimura Y, Chekhoeva A, Oyama K, Nakanishi S, Toshmatova M, Miyahara S, Barth M, Assmann AK, Lichtenberg A, Assmann A, Akhyari P. Controlled autologous recellularization and inhibited degeneration of decellularized vascular implants by side-specific coating with stromal cell-derived factor 1α and fibronectin. Biomed Mater. 2020 Apr 29;15(3):035013.
  7. Toshmatova M, Nakanishi S, Sugimura Y, Schmidt V, Lichtenberg A, Assmann A, Akhyari P. Influence of Laminin Coating on the Autologous In Vivo Recellularization of Decellularized Vascular Protheses. Materials (Basel). 2019 Oct 15;12(20):3351.
  8. Assmann A, Struß M, Schiffer F, Heidelberg F, Munakata H, Timchenko EV, Timchenko PE, Kaufmann T, Huynh K, Sugimura Y, Leidl Q, Pinto A, Stoldt VR, Lichtenberg A, Akhyari P. Improvement of the in vivo cellular repopulation of decellularized cardiovascular tissues by a detergent-free, non-proteolytic, actin-disassembling regimen. J Tissue Eng Regen Med. 2017 Dec;11(12):3530-3543.
  9. Sugimura Y, Schmidt AK, Lichtenberg A, Assmann A, Akhyari P. A Rat Model for the In Vivo Assessment of Biological and Tissue-Engineered Valvular and Vascular Grafts. Tissue Eng Part C Methods. 2017 Dec;23(12):982-994.
  10. Miyahara S, Jenke A, Yazdanyar M, Kistner J, Immohr MB, Sugimura Y, Aubin H, Kamiya H, Okita Y, Lichtenberg A, Akhyari P. The combination approach with Rhokinase inhibition and mechanical circulatory support in myocardial ischemia-reperfusion injury: Rho-kinase inhibition and ventricular unloading. Asian Cardiovasc Thorac Ann. 2022 Oct;30(8):894-905.
  11. Jenke A, Yazdanyar M, Miyahara S, Chekhoeva A, Immohr MB, Kistner J, Boeken U, Lichtenberg A, Akhyari P. AdipoRon Attenuates Inflammation and Impairment of Cardiac Function Associated With Cardiopulmonary Bypass-Induced Systemic Inflammatory Response Syndrome. J Am Heart Assoc. 2021 Mar 16;10(6):e018097.
  12. Pinto A, Immohr MB, Jahn A, Jenke A, Boeken U, Lichtenberg A, Akhyari P. The extracellular isoform of superoxide dismutase has a significant impact on cardiovascular ischaemia and reperfusion injury during cardiopulmonary bypass. Eur J Cardiothorac Surg. 2016 Dec;50(6):1035-1044.
  13. Immohr MB, Dos Santos Adrego F, Teichert HL, Schmidt V, Sugimura Y, Bauer S, Barth M, Lichtenberg A, Akhyari P. 3D-bioprinting of aortic valve interstitial cells: impact of hydrogel and printing parameters on cell viability. Biomed Mater. 2022 Nov 11;18(1).
  14. Selig JI, Krug HV, Küppers C, Ouwens DM, Kraft FA, Adler E, Bauer SJ, Lichtenberg A, Akhyari P, Barth M. Interactive contribution of hyperinsulinemia, hyperglycemia, and mammalian target of rapamycin signaling to valvular interstitial cell differentiation and matrix remodeling. Front Cardiovasc Med. 2022 Oct 31;9:942430.
  15. Barth M, Mrozek L, Niazy N, Selig JI, Boeken U, Sugimura Y, Kalampokas N, Horn P, Westenfeld R, Kröpil P, Aubin H, Lichtenberg A, Akhyari P. Degenerative changes of the aortic valve during left ventricular assist device support. ESC Heart Fail. 2022 Feb;9(1):270-282.
  16. Selig JI, Boulgaropoulos J, Niazy N, Ouwens DM, Preuß K, Horn P, Westenfeld R, Lichtenberg A, Akhyari P, Barth M. Crosstalk of Diabetic Conditions with Static Versus Dynamic Flow Environment-Impact on Aortic Valve Remodeling. Int J Mol Sci. 2021 Jun 28;22(13):6976.
  17. Selig JI, Ouwens DM, Raschke S, Thoresen GH, Fischer JW, Lichtenberg A, Akhyari P, Barth M. Impact of hyperinsulinemia and hyperglycemia on valvular interstitial cells – A link between aortic heart valve degeneration and type 2 diabetes. Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2526-2537.
  18. Barth M, Selig JI, Klose S, Schomakers A, Kiene LS, Raschke S, Boeken U, Akhyari P, Fischer JW, Lichtenberg A. Degenerative aortic valve disease and diabetes: Implications for a link between proteoglycans and diabetic disorders in the aortic valve. Diab Vasc Dis Res. 2019 May;16(3):254-269.
  19. Weber A, Barth M, Selig JI, Raschke S, Dakaras K, Hof A, Hesse J, Schrader J, Lichtenberg A, Akhyari P. Enzymes of the purinergic signaling system exhibit diverse effects on the degeneration of valvular interstitial cells in a 3-D microenvironment. FASEB J. 2018 Aug;32(8):4356-4369.